ASUS S501MD

Create. Produce. Play.

An ASUS S501MD is placed on a wooden table, with a monitor placed on its left hand side.
ASUS S501MD is a powerful, stylish and versatile home desktop PC that’s ideal for a wide range of uses from everyday content creation and home working to online learning and casual gaming. It features a cutting-edge 12th Gen Intel® Core™ processor and high-performance discrete graphics, two-way AI noise cancellation and an optimized thermal system, to keep things quick, clear and cool. It’s manufactured with outstanding build quality for years of durable, reliable computing, and finished with an aesthetically-pleasing geometric design delivers a contemporary look to complement any modern home.

Productivity

Powerful performance, whatever the task

ASUS S501MD makes light work of all your tasks, with a cutting-edge 12th Gen Intel® Core™ processor that delivers enough power for efficient work and optional professional-grade graphics cards to handle demanding intensive-graphic tasks. Up to three displays can be used simultaneously without adding an extra graphics card. Paired with up to 64 GB DDR4-3200 memory, you’ll enjoy lag-free multitasking when running all your applications and files.
An ASUS S501MD is shown next to three adjacent displays that are powered by the computer.
Windows 11 Pro
 
12th Gen
Intel® CPU
Up to
64 GB
DDR4 RAM
Up to
2 TB + 1 TB
HDD + SSD

Graphics

Professional grade graphics

Designed for professionals, ASUS S501MD gives you a wide range of professional graphics choices. From video editing to 3D modeling, select your choice of discrete graphics to empower your creativity.
An ASUS S501MD is placed on the left to a monitor, with video editing software displayed on the screen.
Realize your full potential with Intel® Arc™ graphics
ASUS S501MD is available with Intel® Arc™ A380 discrete graphics. This is powered by the gaming-optimized Xe HPG microarchitecture and enables Xe Super Sampling (XeSS) — Intel’s AI-enhanced technology for high-fidelity visuals with astonishing ray-tracing effects. Further enhanced by the power of a high-performance Intel® Core™ processor, Intel® Arc™ graphics leverage the Intel® Hyper Encode feature to turbocharge every encoding task. All this adds up to accelerated performance and efficiency for content creation, video editing and more.
An ASUS S501MD is placed on the right to a monitor, with architectural design software displayed on the screen.
Elevate your craft with NVIDIA graphics
ASUS S501MD is available with professional-grade NVIDIA GeForce® graphics — based on the cutting-edge NVIDIA Turing™ architecture — to help you seamlessly and effortlessly edit your creations and multilayered files, whether you’re creating short online videos, full-length features, animation or 3D modeling, or exploring graphic design. Render quicker, broadcast clearer, and edit videos better with NVIDIA GPUs in Studio desktops.

Storage

Dual drives for both fast and high-capacity storage

The dual-storage design gives you the best of both worlds — the superfast data-access speeds of an SSD combined with the massive capacity of an HDD. You can have high productivity and efficiency with fast file access in seconds and effortless data storage for large files, applications, and media libraries.
A man is analyzing data through looking at the monitor that is power by an ASUS S501MD on his left-hand side.
Up to
1 TB + 2 TB
PCIe® x4 SSD + HDD

Video Conference

Next-level AI noise-canceling audio technology

To level up professional conferencing, ASUS S501MD has AI-powered noise-canceling technology that employs sophisticated machine-learning techniques. The technology includes both an upstream function to filter noise around the speaker, and a downstream function to eliminate noise from the person at the other end of the conversation. This ensures minimal distraction for high-quality communication, so it’s just like being in the room with other people.
A women is learning lesson through looking at the monitor that is powered by an ASUS S501MD on his right hand side
Ai Noise icon
A women is learning lesson through looking at the monitor that is powered by an ASUS S501MD on his right hand side

Gaming

Fast and fluid

Smooth, clear graphics are crucial in eSports, where reaction times make or break plays. ASUS S501MD has an up to an NVIDIA® GeForce RTX™ 3060 discrete graphics card to pump out reliably high frame rates for fast and fluid gameplay.
A man is playing video game through the monitor that is powered by an ASUS S501MD on his left-hand side.
Up to
GeForce® RTX 3060
NVIDIA® graphics

Design

The PC that’s part of your décor

Every aspect of ASUS S501MD has been carefully thought out to create a balanced design. Its unique outlook, inspired by modern geometric architecture, carries a contemporary 3D triangular pattern and intricate texture to complement any interior space — and is ideal for the home or small studio. This design is more than aesthetically pleasing: the tilted chassis enables increased airflow through the base, improving cooling for smooth performance even under heavy loads.
A front view of the ASUS S501MD is shown against a geometric backdrop.
Side view of an ASUS S501MD with cold air flowing from the side into the fan and air chamber while waste heat flowing out, exiting from the back of the chassis.
Less heat, more productivity
A comprehensive cooling system is essential for the reliable and sustained high performance needed for content creation, multitasking and gaming. With smart component placement that minimizes the space between the CPU and system fans and the tilted chassis that enables increased airflow through the base, ASUS S501MD is able to cool things more efficiently than competing designs — and keep them cool. This enables processor clocks and frequencies to be pushed higher for better overall performance.

Connectivity

Comprehensive, hassle-free connections

With a total of eight USB ports, ASUS S501MD makes it easy to upload and transfer files or connect to external devices. Four front-mounted ports make it even more convenient for you to hook up external drives, cameras or mobile devices without having to reach around the back of the PC.
The front and rear of ASUS S501MD is shown, with all the ports and connections labelled. From top to bottom, left to right. On the back side, there are PS/2 Mouse port, PS/2 Keyboard port, Display port, HDMI port, VGA port, 2USB 3.1 Gen1 port, LAN (PJ-45) port, 2 USB 2.0 port, Microphone port, Line out port, Line in port, Parallel port, Serial port. On the front side, there are Optical disk driver bay , Microphone port, Headphone port, 2 USB2.0 port, an option of 2 USB 3.2 Gen1 port or USB3.2 Gen1 port plus USB Type-CThe front and rear of ASUS S501MD is shown, with all the ports and connections labelled. From top to bottom, left to right. On the back side, there are PS/2 Mouse port, PS/2 Keyboard port, Display port, HDMI port, VGA port, 2USB 3.1 Gen1 port, LAN (PJ-45) port, 2 USB 2.0 port, Microphone port, Line out port, Line in port, Parallel port, Serial port. On the front side, there are Optical disk driver bay , Microphone port, Headphone port, 2 USB2.0 port, an option of 2 USB 3.2 Gen1 port or USB3.2 Gen1 port plus USB Type-C

Reliability

Engineered to last

ASUS S501MD is engineered to deliver reliable long-term operation, offering reassurance that your investment is sound. To achieve this goal, we choose world-leading components renowned for their dependable quality and exceptional endurance.
An ASUS motherboard in black and a CPU highlighted in orange overlay in the center.
World’s #1 motherboards
All ASUS PCs use ASUS motherboards — the world’s #1 motherboard brand — which are renowned for offering comprehensive system protection to safeguard hardware, 24/7 stability through extensive testing, and consistent performance.
Bar chart comparing the power usage between 80 PLUS and 80 PLUS Bronze-certified devices.
The power wasted by an 80 PLUS Bronze-certified device is 15% of its total power consumption, and this is 5% lower than standard 80 PLUS-certified device.
Power up everything
ASUS S501MD features a high-efficiency 80 PLUS® Bronze-certified power supply. Engineered with top-end capacitors for maximum durability, this enables the PC to deliver power at an efficiency of up to 85% — resulting in less heat and lower long-term running costs.
Nine gold-colored solid capacitors in two runs, running diagonally from the bottom left to top-right corner
Industry-leading MTBF
All ASUS PCs offer 100% solid capacitors, which are important for storing charge and regulating voltage. This increases system stability, thermal capacity and longevity, resulting in a top-tier Mean Time Between Failures (MTBF) rating.

Reliability

Built for the long term

ASUS desktop PCs are subjected to a series of rigorous noise, vibration, drop and thermal-shock tests to ensure they meet our exacting standards, and exceed those set by other manufacturers. Rest assured that ASUS S501MD can cope with temperature extremes and the bumps and knocks of shipping.
Shock Test
Vibration Test
Altitude Storage Test
Altitude Test
High Temperature Test
High Temperature Storage Test
Low Temperature Test
Low Temperature Storage Test
Humidity Test
  1. ASUS secured the #1 spot for motherboard market share as of 2017, with DigiTimes reporting that the Taiwanese PC component giant owns 45% of the motherboard market.
Related products
ASUS A3202
ASUS A3202
ASUS A3202
21.45

ASUS A3202

0.0 out of 5 stars.
  • Windows 11 Home - ASUS recommends Windows 11 Pro for business
  • Up to 12th Gen Intel® Core™ i7 processor
  • Full HD (1920 x 1080) anti-glare panel
  • Slim bezel, 86% screen-to-body ratio
  • 2GB DDR4 3200Mhz memory
  • 512GB M.2 PCIe SSD + 1TB HDD storage
  • ASUS SonicMaster Premium audio
  • Two-way AI-powered noise cancelation
Learn more
ASUS A3402
ASUS A3402
ASUS A3402
24"

ASUS A3402

0.0 out of 5 stars.
  • Windows 11 Pro - ASUS recommends Windows 11 Pro for business
  • Up to 12th Gen Intel® Core™ i7 processor
  • Full HD (1920 x 1080) anti-glare panel
  • Slim bezel, 88% screen-to-body ratio
  • 2GB DDR4 3200Mhz memory
  • 512GB M.2 PCIe SSD + 1TB HDD storage
  • HDMI-in for flexible usage
  • Two-way AI-powered noise cancelation
Learn more
ASUS Vivobook 15 OLED (X1505)
ASUS Vivobook 15 OLED (X1505)
ASUS Vivobook 15 OLED (X1505)
15.6”

ASUS Vivobook 15 OLED (X1505)

  • Windows 11 Home - ASUS recommends Windows 11 Pro for business
  • Up to 13th Intel® Core™ i9 processor
  • Up to 15.6” 2.8K OLED NanoEdge display
  • Up to 16 GB DDR4 memory
  • Up to 1 TB SSD storage
  • Optional fingerprint login sensor
  • ASUS Antimicrobial Guard Plus
  • Military-Grade durability
Learn more
VivoBook 14 (X1400, 11th gen Intel)
VivoBook 14 (X1400, 11th gen Intel)
VivoBook 14 (X1400, 11th gen Intel)
14"

VivoBook 14 (X1400, 11th gen Intel)

  • Windows 11 Home - ASUS recommends Windows 11 Pro for business
  • Up to 11th Intel® Core™ i7 processor
  • Up to NVIDIA® GeForce® MX330
  • Up to 16 GB DDR4 memory
  • Up to 1 TB HDD + 1 TB SSD
  • Up to 14'' FHD NanoEdge display
  • Optional ASUS NumberPad 2.0
  • Intel® Optane™ memory support
Learn more
ASUS ExpertCenter E1 AiO (E1600)
ASUS ExpertCenter E1 AiO (E1600)
ASUS ExpertCenter E1 AiO (E1600)
15.6”

ASUS ExpertCenter E1 AiO (E1600)

  • Windows 11 Pro - ASUS recommends Windows 11 Pro for business
  • Up to Intel® Celeron® processor
  • Up to Intel® UHD graphics
  • Up to 8 GB memory
  • Up to 256 GB SSD + 1 TB HDD storage
  • 15.6” HD display
  • Uninterruptible power supply (UPS) system
  • Fanless design, VESA compatible
Learn more
ASUS ProArt Station PD5 PD500TC
ASUS ProArt Station PD5 PD500TC
ASUS ProArt Station PD5 PD500TC
29L

ASUS ProArt Station PD5 PD500TC

  • Windows 11 Pro - ASUS recommends Windows 11 Pro for business
  • Up to 11th gen Intel® Core™ i9 processor
  • Up to NVIDIA® GeForce® RTX 3070 or NVIDIA® RTX A2000
  • Up to 128 GB memory
  • Up to 4 TB HDD + 2 TB SSD storage
  • ISV certification
  • Lumiwiz® Smart LED indicators
Learn more
ExpertCenter E5 AiO 22
ExpertCenter E5 AiO 22
ExpertCenter E5 AiO 22
23.8”

ExpertCenter E5 AiO 22

  • Windows 10 Pro
  • Up to 11th Intel® Core™ i7 processor
  • Up to 32 GB memory
  • Up to 1 TB HDD + 512GB SSD storage
  • Up to 21.5" FHD NanoEdge display
  • NanoEdge 84% screen-to-body ratio
  • two-way AI noise-canceling technology
  • Optional customer-facing second screen
Learn more
ExpertBook B1 B1500
ExpertBook B1 B1500
ExpertBook B1 B1500
15.0"

ExpertBook B1 B1500

0.0 out of 5 stars.
  • Windows 11 Pro - ASUS recommends Windows 11 Pro for business
  • Up to 11th Intel® Core™ i7 processor
  • Up to NVIDIA® GeForce® MX330
  • Up to 48 GB memory
  • Up to 1 TB HDD + 512GB SSD storage
  • Up to 14" FHD NanoEdge display
  • NanoEdge 90% screen-to-body ratio
  • Optional fingerprint sensor login
Learn more
ASUS V241 (11th Gen Intel)
ASUS V241 (11th Gen Intel)
ASUS V241 (11th Gen Intel)
23.8"

ASUS V241 (11th Gen Intel)

  • Windows 10 Home - ASUS recommends Windows 11 Pro for business, Free Upgrade to Windows 11¹ (when available, see below)
  • Up to 11th Intel® Core™ i7 processor
  • Up to NVIDIA® GeForce® MX330
  • Up to 16 GB memory
  • Up to 1 TB HDD + 512GB SSD storage
  • Up to 23.8'' FHD NanoEdge display
  • Multi-touch screen
  • 178° wide viewing angle
Learn more
previous image
next image
comparison icon
Compare (0)