AMD TRX40 ATX motherboard sTRX4 for 3rd Gen Ryzen Threadripper-series processors (up to 64 cores) with 16 power stages, DDR4 4666+ MHz (O.C.), triple PCIe 4.0 M.2s, USB 3.2 Gen 2 Type-C front-panel connector and Aura Sync RGB lighting
  • AMD Socket sTRX4: Ready for the latest 3rd Gen AMD Ryzen™ Threadripper™ series processors (support up to 64 cores)
  • Robust power design: 16 power stages, ProCool II connectors with solid pins, and premium chokes and capacitors for stable power delivery
  • Comprehensive thermal solutions: VRM heatsink, M.2 heatsink, SoC VRM heatsink, active chipset heatsink solution, and an array of hybrid fan headers
  • Next-gen connectivity: Three PCIe 4.0 NVMe M.2 slots, USB 3.2 Gen 2 Type-C™ front-panel connector, and Intel Gigabit Ethernet
  • Intelligent tuning: ASUS 5-Way Optimization software and renowned UEFI BIOS offer easy configuration options for all experience levels
Win11
PRIME TRX40-PRO S
PRIME TRX40-PRO S front view
TUF H370 Plus Gaming TUF H370 Plus Gaming
  • 6 x USB 3.2 Gen 1

  • BIOS FlashBack Button

  • 4 x USB 3.2 Gen 2
    (3 x Type-A & 1 x Type-C™)

  • Intel® Gb Ethernet

  • 8-Channel HD Audio

  • 3 x PCIe 4.0 (x16/x16/x16)
    ● 2-Way SLI & 2-Way CFX Support
    ● ASUS SafeSlot

  • Crystal Sound 3
    ● Realtek® S1220 Codec
    ● Power Pre-Regulator
    ● De-Pop Circuit
    ● Audio Shielding
    ● Premium Japanese
    Audio Capacitors
    ● Dedicated Audio
    PCB Layers
    ● DTS:X® Ultra

  • 2 x 8-Pin ProCool II Connectors

  • 16 Power Stages

  • 4-Pin RGB Header

  • Addressable Gen 2 RGB Header

  • DDR4 4666+ (O.C.)

  • AMD Socket sTRX4 for 3rd Gen
    AMD Ryzen Threadripper
    Series Processors

  • Vertical M.2 22110
    (PCIe 4.0 x4 & SATA Modes)

  • USB 3.2 Gen 2 Type-C
    Front-Panel Connector

  • AMD TRX40 Chipset

  • 2 x M.2 22110
    (PCIe 4.0 x4 Mode)

  • 8 x SATA 6Gb/s

  • Addressable Gen 2 RGB Header

  • 4-Pin RGB Header

Prime

ASUS Prime TRX40-Pro S is expertly engineered to unleash the full potential of AMD's latest high-core-count processors for content creators, designers and professional use. Combining a robust power design, comprehensive cooling solutions, ultrafast PCIe 4.0 connectivity and intelligent tuning options, the high-end desktop motherboard delivers the performance and stability needed to turn every creative vision into reality.

Get the Most out of All Your Cores

AMD's HEDT platform raises the stakes with the latest AMD 3rd Gen Ryzen Threadripper processors that boast more cores and higher bandwidth than ever before. Prime TRX40-Pro S is ready for the additional processing power that plows through intensive tasks such as 3D rendering and video editing, and the extra bandwidth allows you to add multiple graphics cards and NVMe SSDs to accelerate your productivity.

ProCool II Connectors

ProCool II connectors ensure a snug and reliable connection to the EPS 12V power lines. The second-generation features upgrades of metal amour and solid pins for better heat dissipation, as well as a warning LED-display with a BIOS POST message to indicate improper connections.

16 Power Stages

Prime TRX40-Pro S's VRM is comprised of 16 power stages, delivering the power and efficiency that the latest AMD processors demand.

Premium Chokes and Caps

Superior chokes and durable caps are engineered to resist extreme temperatures and provide better performance.

Back to Get the Most out of All Your Cores
Learn more to protect your graphics card investment
Back to Get the Most out of All Your Cores

Triple PCIe 4.0 M.2

Serious Speed with Onboard M.2

Professional content creation applications require fast solid-state storage, which is why Prime TRX40-Pro S is equipped with three PCIe 4.0 M.2 slots that are compatible with the latest NVMe SSDs. All slots support up to 110 mm drives, and they can be configured into bootable RAID arrays for ultrafast data-transfer speeds.

Back to Get the Most out of All Your Cores

USB 3.2 Gen 2 Type-C Front-Panel Connector

Future-Proof Connectivity

Plenty of USB ports are provided to support high-end rigs loaded with peripherals, including a front-panel Type-C connector with faster USB 3.2 Gen 2 connectivity for compatible cases.

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Intel Ethernet

More Throughput, Less CPU Usage

The latest Intel® I211-AT Ethernet has the advantage of reducing CPU overhead and offering exceptionally high TCP and UDP throughput for faster, smoother data transfer.

Lower CPU workloadHigh TCP & UDP throughput
Learn more on hardware-level networking protection and optimization software

LANGuard

Pumped-Up Throughput. 2.5X-Higher Surge Tolerance.

ASUS LANGuard is a hardware-level networking protection that employs signal-coupling technology and premium anti-EMI surface-mounted capacitors to ensure a more reliable connection and better throughput.

Turbo LAN

Network-Optimization Software for Customizable Packet Prioritization

Turbo LAN with cFosSpeed traffic-shaping technology allows you to configure application priority via an intuitive interface and reduces network lag.

Back to Get the Most out of All Your Cores

Cool to the Core

Effective content creation demands a reliable, professional foundation. Prime TRX40-Pro S is engineered with multiple onboard heatsinks and an array of hybrid fan headers to ensure your rig stays cool and stable under intense workloads, so that your focus remains fixed on your creative goals.

M.2 Heatsink

Two M.2 slots are covered by a massive heatsink to combat temperature-induced throttling that can affect performance during heavy, sustained storage loads.

Removable captive screws reduce risk of drops or losses during heatsink removal

VRM Heatsink and Thermal Pads

A massive VRM heatsink and high-quality thermal pads enhance heat transfer from the MOSFETs and chokes for better cooling performance. A fan holder is bundled for additional cooling options.

SoC VRM Heatsink

Prime TRX40-Pro S features an SoC VRM heatsink, positioned in the pathway of the chipset fan's airflow, to enable the SoC VRM to stay cool during memory overclocking.

Active Chipset Heatsink Solution

Dedicated Cooling for Unthrottled Transfers

PCIe 4.0 provides twice the bandwidth for data flowing through the chipset, which creates more heat than the previous generation. Prime TRX40-Pro S features an actively cooled heatsink to prevent throttling during sustained transfers, designed with the screws on top for easy access and maintenance.

Active Chipset Heatsink Solution includes:

  • Air Duct: A specially-designed air duct helps the fan generate static pressure and concentrates air flow over the fins.
  • Finned Heatsink: The heatsink fin density is optimized to maximize surface area while maintaining a low-resistance exhaust path.
  • Custom Delta Superflo Fan: The custom low-noise fan features a high-durability bearing with a 60,000-hour L10* lifespan, while its speed is easily adjusted via Fan Xpert 4 or the UEFI.

* L10 bearing life is a standard metric that specifies the number of hours that 90% of the bearing are expected to continue successfully operating, as a minimum.


Back to Cool to the Core

Cooler by Design

Prime TRX40-Pro S features the most comprehensive cooling controls ever, configurable via Fan Xpert 4 or the UEFI BIOS.

  • Multiple Temperature Sources
  • Dual Pump Headers
  • Smart Protection
  • 4-Pin PWM/DC Fan
  • Each header can dynamically reference three thermal sensors, and via Fan Xpert 4 you can even map the temperature of supported ASUS graphics cards to optimize cooling for GPU- and CPU-intensive tasks.

  • A dedicated header that supplies over 3A for high-performance PWM or DC water pumps, plus a second dedicated header for AIOs.

  • A dedicated integrated circuit that protects each fan header from overheating and overcurrent.

  • Each onboard header supports auto-detection of PWM or DC fans.

Back to Cool to the Core

Tune It Your Way

Comprehensive controls form the foundation of the ASUS Prime series. Prime TRX40-Pro S packs flexible tools to tune every aspect of your system, enabling you to tweak performance settings to perfectly match the way you work – maximizing your productivity.

5-Way Optimization

One click takes care of all that complex tuning. ASUS 5-Way Optimization makes your PC smart. It dynamically optimizes essential aspects of the system, providing overclocking and cooling profiles that are tailored for your rig.

  • An automated tuning utility that optimizes overclocking and cooling profiles for your unique system configuration.
  • Fans stay quiet as a whisper for everyday computing, and deliver optimal airflow when the system is crunching through CPU- or GPU-intensive tasks.
  • The stress test allows you to optimize and overclock for CPU- or memory-centric workloads.

CPU Performance Boost

The TurboV Processing Unit (TPU) is the intelligence behind our automated system-tuning utility, offering the ability to fine-tune voltages, monitor system stats, and adjust overclock parameters for optimal performance.

All-Around Energy Efficiency

With the Energy Processing Unit (EPU), you'll enjoy system-wide power savings. The EPU automatically optimizes power consumption and maximizes savings with the Away mode.

Flexible Cooling Controls for Air or Liquid

With Prime TRX40-Pro S, you have comprehensive control over fans via Fan Xpert 4 or UEFI. Whether you're cooling with air or water, Auto-Tuning mode intelligently configures all parameters with a single click. There's also an Extreme Quiet mode, which reduces all fan speeds to below the default minimum – keeping your system quiet as a whisper when performing light tasks.

Precise Digital Power Control

The Digi+ voltage-regulator module (VRM) delivers a real-time control over voltages, switching frequency and power-efficiency settings, allowing you to fine-tune your CPU for ultimate stability and performance.

App-Specific Optimization

Turbo App allows you to define CPU overclocking, apply fan profiles, prioritize network data and optimize audio setting at app level, meaning your system is perfectly optimized for what you're doing.

Back to Tune It Your Way

UEFI BIOS

The renowned UEFI BIOS provides everything you need to configure, tweak, and tune your rig. It offers intelligently simplified options for newcomers to PC DIY, as well as comprehensive features for seasoned veterans.

Advanced Tuning for Serious Tweakers

When you're ready to take a deeper dive into the configuration of your rig, Advanced Mode grants total control. Each section is intuitively organized, and a built-in search feature makes it easy to find the option you need. Tweak cooling parameters, save profiles, apply overclocks, and unleash the full potential of the latest Ryzen processor.

FlexKey
The FlexKey offers a new option to remap the system reset button on the chassis to toggling Aura lighting on/off or boot directly into the UEFI.

Search Function
Quickly and easily find the option or setting that you're looking for.

ASUS User Profile
Port configuration settings between different BIOS versions or share them with friends.

My Favorites
Quickly discover tuning options and add preferred tools to the list.

Quick and Simple Setup

Designed to simplify setup, EZ mode presents all the vital settings and stats on one single page. With guided wizards, drag-and-drop functionality, and one-click application of important settings, your rig will be up and running in no time.

Intuitive Graphical Fan Control
Fine-tune individual fans simply by dragging a curve with the mouse.

EZ DOCP
Improve DRAM performance with one click.

Aura On/Off Mode (Stealth)
Easily enable or disable Aura RGB lighting or every onboard LED, for a subdued aesthetic touch.

SATA Information
SATA port details that help easily recognize drives.

Back to Tune It Your Way

Little Things Make a Big Difference

We pay careful attention to all the little details that improve your overall experience, from utilizing exclusive codecs for pristine audio quality to intuitive RGB lighting controls for a customized look. Prime TRX40-Pro S provides the tools you need to personalize your build for a more enjoyable creation process.

Pre-Mounted I/O Shield

Set Up without Slip-Ups

Form meets function in the pre-mounted I/O shield that we pioneered with the ROG series motherboards. Now available on Prime TRX40-Pro S, this feature streamlines the installation process for budding builders and savvy enthusiasts alike.

FlexKey

The Chassis Reset Button – Reassigned

Flexkey, a front-panel header lets you customize the reset button on the front-panel of your chassis to provide quick access to our choice of Aura lighting controls, DriectKey or system reset.

BIOS FlashBack™

Update Your BIOS Without CPU and DRAM

BIOS FlashBack is the simplest and safest (UEFI) BIOS update method. Simply drop the (UEFI) BIOS file onto a FAT32-formatted USB stick, plug it into the USB BIOS FlashBack port and press the button. Updates can even be performed without having memory or a CPU installed.

Back to Little Things Make a Big Difference

Realtek Codec and Unique Design Features for Pristine, Powerful Audio

Prime TRX40-Pro S utilizes a unique audio codec designed in close collaboration with Realtek — the Realtek S1220. It also features an unprecedented 120dB signal-to-noise ratio for the stereo line-out and a 108dB SNR for the line-in, providing pristine audio quality. Additionally, a new impedance-sensing circuit automatically adjusts the gain to ensure optimal volume range for your headphones.

DTS:X® Ultra adds a spatial audio feature to boost headphones and speakers for enhanced gaming, VR, and extended-reality experiences. DTS:X Ultra supports sound based on channels, scenes, and objects to allow for deeper sonic immersion in enabled content. It also provides post-processing enhancements and device-level tuning for DTS® codecs.


Flawless Audio that Immerses You in the Game

Power Pre-Regulator

Reduces power-input noise to ensure consistent performance.

Audio Shielding

Separates analog/digital signal domains, significantly reducing multi-lateral interference.

Separate Layer for Left and Right Tracks

Ensures minimal crosstalk between audio paths.

Integrated Amplifier

Capable of driving high-impedance headphones, without rolling-off high or low frequencies.

De-Pop Circuit

Reduces start-up popping noise to all audio outputs.

Premium Japanese Capacitors

Premium parts provide an immersive sound signature, with exceptional fidelity.

Back to Little Things Make a Big Difference

Aura Sync

Outshine the Competition

A well-tuned enthusiast system deserves a matching aesthetic. ASUS Aura offers full RGB lighting control with a variety of functional presets for the built-in RGB LEDs as well as strips and devices connected to the onboard RGB headers – and they can all be synced with an ever-growing portfolio of Aura-capable hardware.

Learn more >
  • Static Static
  • Breathing Breathing
  • Strobing Strobing
  • Rainbow Rainbow
  • Color cycle Color Cycle
  • Starry night Starry Night
  • Music effect Music Effect
  • CPU temperature Smart

Addressable Gen 2 RGB Header

Prime TRX40-Pro S has two Addressable Gen 2 RGB Headers, which are now capable of detecting the number of LEDs on second-gen addressable RGB devices, allowing the software to automatically tailor lighting effects to specific devices. The new headers also offer backward-compatibility with existing Aura RGB gear.

Armoury Crate

Armoury Crate is a new software utility designed to give you centralized control of supported products. From a single intuitive interface, Armoury Crate allows you to easily customize RGB lighting and effects for every compatible device in your arsenal. The software also provides control of settings for ASUS products, including keyboard and mouse preferences. Armoury Crate even features dedicated product registration and highlight to help you stay in touch with the ASUS community.


  • Aura Sync

  • Driver & Manual Download

  • Account Management

Back to Little Things Make a Big Difference

The Power of AMD

AMD TRX40 Chipset

The AMD TRX40 chipset delivers outstanding overclocking capabilities for the latest AMD Socket sTRX4 3rd Gen Ryzen Threadripper series processors. It provides PCIe 4.0 support, 10 Gbps USB 3.2 Gen 2 ports, and eight SATA 6 Gbps ports for faster data retrieval.

Ready for AMD Socket sTRX4 3rd Gen Ryzen Threadripper

ASUS Prime TRX40-Pro S motherboard supports the latest 3rd Gen AMD Ryzen Threadripper series processors that boast up to 64 cores. It features quad-channel DDR4 memory, 64 lanes of PCI Express® 4.0, 16 GT/s transfer speed for Gen 4 M.2 SSDs, and built-in native USB 3.2 Gen 2 (10 Gbps) for superior performance.

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