ASUS S500ME

Where to buy

ASUS S500ME

Work and play, empowered

An ASUS S500ME is placed on a wooden table in the living room, with a monitor on its left-hand side.
With the latest-generation processors, fast discrete graphics and DDR4 memory, ASUS S500ME is the family PC that maximizes performance in minimal space, enabling you to power through everyday tasks — anywhere in your home. Its dual-storage design lets you access your files, photos and multimedia libraries in seconds, while the advanced thermal layout, AI noise-canceling technology and tool-free access design are born to power up your productivity. ASUS S500ME also boasts outstanding build quality inside and out, including an all-solid capacitor design to ensure years of durable and reliable computing.

Performance

Primed for any task

From daily computing tasks like writing reports or surfing the net, to watching videos or playing games with the kids — ASUS S500ME takes it all in its stride. Its latest-generation Intel® Core™ processor and high-speed memory provide fast and responsive performance, while its discrete NVIDIA® graphics card enhances visuals for incredibly-realistic photos and videos.
A man is using an ASUS S500ME to surf the net with his kids at home.
Windows 11 Home
13th Gen
Intel® CPU
Up to
64 GB
DDR4 RAM
Up to
GeForce® RTX 3060
NVIDIA® graphics

Graphics Card

Immersive entertainment

When it’s time to kick back and relax with the family, perhaps by looking through old photos or watching supersmooth 4K UHD movies, ASUS S500ME delivers a high-quality, high-performance entertainment experience. You can even fire up the latest games for immersive, lag-free gaming.
An ASUS S500ME is placed on a white wooden table in the living room. On its left-hand side is a monitor with dolphins jumping out of the screen.
Up to
GeForce® RTX 3060
NVIDIA® graphics

Storage

Dual drives for fast and high-capacity storage

The dual-storage design gives you the best of both worlds: the superfast data-access speeds of an SSD combined with the massive capacity of an HDD. The SSD speeds up your operating system and apps so you can boot up and access files in seconds. And with its high-capacity hard drive, ASUS S500ME has more than enough space for all your photo albums, music and movie libraries.
An ASUS S500ME is placed on the right hand side of the monitor on a wooden table, with different-colored light beams shown on the monitor.
Up to
2 TB + 3 TB
SSD + HDD

Lifelike Visuals

Stunning 4K UHD visuals

Discrete NVIDIA GeForce® RTX™ series takes visuals up a notch, allowing ASUS S500ME to support up to 4K UHD displays. With a resolution of 3840 x 2160 pixels — 4x more than Full HD — everything is pin-sharp, from the finest details in videos and photos to the tiniest text.
A comparison of quality difference between Full HD and 4K UHD, showing that Ultra HD has better quality.
3840 x 2160
4K UHD
4X
more pixels than Full HD

Easy to Use

Easy to use and manage

ASUS S500ME utilizes clever user-centric design details abound to help you upgrade and manage your PCs effortlessly.
A side view of an ASUS S500ME, with green and blue arrows showing the direction to pull out the HDD or ODD by hand.
Hassle-free maintenance and upgrades
ASUS S500ME has a tool-free chassis design so you can open it up with no tools required. The HDD and ODD can also be easily pulled out with just fingers. This saves time and effort, making component upgrades and routine servicing easy.

Design

Designed to go beyond

From an advanced thermal design to the power supply, ASUS S500ME provides safer and smoother experiences for daily computing and enjoyment.
Side view of an ASUS S500ME with cold air flowing from the front panel into the fan and air chamber, while waste heat exiting from the back panel.
Less heat, more productivity
To ensure stable performance in the compact chassis, ASUS S500ME employs an innovative multi-channel cooling system. This comprises dedicated, isolated air chambers that allow independent heat-venting channels for the PC’s main thermal generators — the CPU, GPU and power supply. ASUS S500ME also includes the exclusive MyASUS app to optimize the operation of the CPU and system fans, automatically moderating the speeds and switching them off completely when possible, striking the perfect balance between maximum performance and minimum noise.
Bar chart comparing the power usage between 80 PLUS and 80 PLUS Bronze-certified devices. The power wasted by an 80 PLUS Platinum -certified device is 8% of its total power consumption, and this is 12% lower than standard 80 PLUS-certified device.
Efficient power consumption
ASUS S500ME features a high-efficiency 80 PLUS® Platinum-certified power supply. Engineered with top-end capacitors for maximum durability, this enables ASUS S500ME to deliver power at an efficiency of up to 92% — resulting in less heat and lower long-term running costs.
Nine gold-colored solid capacitors in two runs, running diagonally from the bottom left to top-right corner.
Safer and more durable components
All ASUS PCs use 100% enterprise-grade solid capacitors in their motherboards. These capacitors are able to withstand extreme temperatures, ensuring smooth and stable performance, even after many hours of use.

Noise Cancelation

Two-way AI noise-canceling audio technology

To level up professional conferencing, ASUS S500ME has AI-powered noise-canceling technology that employs sophisticated machine-learning techniques. The technology includes both an upstream function to filter noise around the speaker, and a downstream function to eliminate noise from the person at the other end of the conversation. Try the demo to experience the amazing difference that ASUS AI noise-canceling technology can make.

Connectivity

Comprehensive, hassle-free connections

With a total of eight USB ports, ASUS S500ME makes it easy to upload and transfer files or connect to external devices. Four front-mounted ports make it even more convenient for you to hook up external drives, cameras or mobile devices without having to reach around the back of the PC.
The rear and front of ASUS S500ME is shown, with all the ports and connections labelled. From top to bottom, left to right. On the rear side, there are: PS/2 Keyboard Port , PS/2 Mouse Port, Parallel Port, HDMI Port, VGA Port, four USB 2.0 Port, LAN (RJ-45) Port, microphone Port, Line-out Port, Line-in Port, two Serial Ports. On the front side, there are: Optical Disk Drive Bay, Headphone Port, Audio combo jack, two USB 3.2 Gen 1 ports and two USB 3.2 Gen 2 ports, and a SD card reader.The rear and front of ASUS S500ME is shown, with all the ports and connections labelled. From top to bottom, left to right. On the rear side, there are: PS/2 Keyboard Port , PS/2 Mouse Port, Parallel Port, HDMI Port, VGA Port, four USB 2.0 Port, LAN (RJ-45) Port, microphone Port, Line-out Port, Line-in Port, two Serial Ports. On the front side, there are: Optical Disk Drive Bay, Headphone Port, Audio combo jack, two USB 3.2 Gen 1 ports and two USB 3.2 Gen 2 ports, and a SD card reader.

Reliability

Built for the long term

ASUS desktop PCs are subjected to a series of rigorous noise, vibration, drop and thermal-shock tests to ensure they meet our exacting standards, and exceed those set by other manufacturers. Rest assured that ASUS S500ME can cope with temperature extremes and the bumps and knocks of shipping.
Shock Test
Vibration Test
Altitude Storage Test
Altitude Test
High Temperature Test
High Temperature Storage Test
Low Temperature Test
Low Temperature Storage Test
Humidity Test
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