WS C422 PRO/SE

Intel® LGA2066 ATX motherboard with complete IT infrastructure management supporting Intel® Xeon® processor and ECC memory
  • Powered by Intel® Xeon® W processor with ECC memory
  • ASUS Control Center - A software utility that provides convenient, secure and cost-saving centralized IT management for small and medium businesses
  • Server-grade design with built-in dual Intel Gigabit LAN
  • Next-gen transfer speeds - Up to 32Gbps dual M.2 and U.2, plus up to 10Gbps USB 3.1 Type-A and Type-C connections
  • Ultimate graphics power with 2/3-Way NVIDIA® SLI™ and AMD® Crossfire X™
  • Ultra-efficient VRM heatsink - Metal fin array connected to large surface area via a heatpipe tames C422 thermals to enable unthrottled performance
Win11
WS C422 PRO/SE
WS C422 PRO/SE motherboard, front view


Comprehensive IT Management Software


WS C422 PRO/SE features an embedded iKVM module and is bundled with ASUS Control Center software to provide comprehensive in-band and out-of-band management features for small and mid-size businesses:
ASUS Control Center (ACC) is a centralized and integrated IT management platform for monitoring and controlling ASUS commercial products, including servers, workstations and digital signage. ACC enables remote BIOS updates, monitoring of multiple systems via mobile devices, and one-click software updates and dispatching, allowing easier server management for any IT infrastructure.
The embedded ASMB9-iKVM module supports remote BIOS updates, fans control, standalone KVM, video recording, and BSOD capture, providing around-the-clock remote monitoring and diagnostics — even if the operating system is down or offline — through a user-friendly, web-based graphical interface that works with all major browsers.



Powerful performance with Intel® Xeon® W processor and ECC memory

WS C422 PRO/SE supports server-grade Intel® Xeon® W series processors to deliver powerful, optimized performance in always-on usage scenarios. Support for Error-Correcting Code (ECC) memory enables automatic detection and repair of single-bit memory errors, reducing the chance of system crashes and data corruption to ensure reliable and responsive workstation performance.

Up to 3-way Multi-GPU support with True PCIe Gen3 x 16 link

WS C422 PRO/SE features three true PCIe Gen 3 links with support for two-way and three-way NVIDIA®SLI™ and AMD CrossFireX™ configurations to enable multiple GPU setups that harness the full power of the latest graphics technologies to unleash maximum graphics processing performance.




Ultra-efficient VRM Heatsink

Designed for the powerful Intel® Xeon® scalable processor with up to 28 cores, WS C422 PRO/SE features a capable thermal design to ensure maximum performance with no CPU throttling. Consisting of an ultra-efficient VRM heatsink with a metal fin array design that maximizes surface area for heat dissipation, plus two additional heatsinks and a connecting heatpipe to further increase cooling performance, this innovative thermal design ensures WS C422 PRO/SE is always ready to handle any task, no matter how demanding.

Ultra-fast storage and I/O options

Dual onboard M.2 & M.2 heatsink

WS C422 PRO/SE features dual onboard M.2 slots that support up to 22110-length SSDs and operate at PCIe Gen 3 x4 link speeds to provide an abundant 32Gbps of bandwidth for up to 5.3X faster performance than traditional SSDs. Both slots sit below the C422 chipset and are covered by a heatsink that reduces drive temperatures by as much as 20°C, ensuring peak performance under all scenarios. The revolutionary specification that lets your SSDs scream at top speed. Simply attach your choice of drive and experience data-transfer speeds of up to 32Gbps — and free up a PCIe slot for another expansion card.


10Gbps USB 3.1 onboard

With backward-compatible USB 3.1 Type-A and reversible USB 3.1 Type-C ports, you'll experience ultimate connection flexibility and data-transfer speeds of up to 10Gbps — twice as fast as USB 3.0.


  • - Front panel : 2 x USB 3.1
    (Type A and Type C)
  • - Rear panel : 1 x USB 3.1



Supporting ThunderboltEX 3 card

WS C422 PRO/SE provides full support for a ThunderboltEX 3 card. An Intel®-certified Thunderbolt™ 3 add-on card enables breathtaking bi-directional speeds of up to 40Gbps through a single cable — up to 4X faster than other PC data-transfer protocols. Beyond sheer bandwidth, Thunderbolt™ 3 supports daisy-chaining up to six devices, utilizes a Type-C reversible connector for compatibility with the latest USB 3.1 Gen 2 Type-C devices, and meets USB Power Delivery specifications for fast, high-power charging of up to 36W. Learn More

Intel® VROC

Unleash the WS C422 PRO/SE Virtual RAID on CPU (VROC) with the addition of an ASUS Hyper M.2 X16 card*, which allows you to attach up to four PCIe®3.0 x16 M.2 drives — for a total bandwidth of up to 128Gbps. PCH-based RAID arrays are bottlenecked by the 32Gbps limit of the DMI bus. VROC obliterates that limit by allowing you to utilize CPU PCIe lanes to configure a bootable RAID array that can transfer data at insane speeds.

*ASUS Hyper M.2 X16 card available separately for purchase.




Outstanding Audio for Content Creator

WS C422 PRO/SE has a unique audio codec designed in close collaboration with Realtek®. The Realtek®S1220A features an unprecedented 120dB signal-to-noise ratio for the stereo line-out and an 113dB SNR for the line-in, providing pristine audio quality.

Immersive headphone audio

DTS Headphone:X™

Offers 3D surround-sound technology for incredibly rich audio with all types of headphones.



Dual Intel® server-class Gigabit LAN

For more reliable networking, WS C422 PRO/SE features the latest server-class dual Intel® Gigabit LAN ensuring lower CPU utilization and temperatures outstanding performance as well as better support for diverse operating systems. The dual Ethernet ports also support teaming which combines the network links to provide higher throughput or redundancy in case of failure.



ASUS SafeSlot

SafeSlot is the PCIe slot reinvented by ASUS and engineered to provide superior retention and shearing resistance. Manufactured in a single step using a new insert-molding process, SafeSlot integrates the slot with fortifying metal for an inherently stronger slot, which is then firmly anchored to the PCB through additional solder points.

Recommend for you
award iconaward iconaward icon
Pro WS C422-ACE
Pro WS C422-ACE
Pro WS C422-ACE
Win11
0.0 out of 5 stars.
Intel ATX LGA 2066 Workstation motherboard with PCIe 3.0 x16, 14 power stages, triple M.2 with dual M.2 heatsinks, dual U.2, dual Intel LAN, DDR4 ECC memory support, and ASUS Control Center Express
award iconaward iconaward icon
WS C422 SAGE/10G
Win11
0.0 out of 5 stars.
Intel® LGA2066 CEB motherboard with 4-way SLI graphic power, dual Intel® 10G LAN, dual M.2 & U.2, USB 3.1 Gen2 connectors and ASUS Control Center
award iconaward iconaward icon
WS X299 PRO/SE
WS X299 PRO/SE
WS X299 PRO/SE
Win11
0.0 out of 5 stars.
Intel LGA 2066 ATX motherboard with DDR4 4133MHz, dual M.2 and M.2 heatsink, U.2, USB 3.1 Gen 2 connectors, ASMB9-iKVM and ASUS Control Center.
award iconaward iconaward icon
WS X299 SAGE/10G
WS X299 SAGE/10G
WS X299 SAGE/10G
Win11
0.0 out of 5 stars.
Intel LGA 2066 CEB motherboard with quad-GPU support, DDR4 4200MHz, Dual Intel® 10G LANs, M.2, U.2, USB 3.1 Gen 2 connectors, and ASUS Control Center
award iconaward iconaward icon
Pro WS X299 SAGE II
Pro WS X299 SAGE II
Pro WS X299 SAGE II
Win11
Adobe 3 month bundle
0.0 out of 5 stars.
Intel CEB motherboard LGA 2066 for Intel Core X-series processors, with AI Overclocking, dual Intel 2.5G Ethernet, 7 PCIe Gen 3 slots, DDR4 4266 MHz memory support, dual M.2, triple U.2, USB 3.2 Gen 2 Type-C and Aura Sync RGB lighting
award iconaward iconaward icon
TUF GAMING H470-PRO (WI-FI)
TUF GAMING H470-PRO (WI-FI)
TUF GAMING H470-PRO (WI-FI)
Win11
0.0 out of 5 stars.
Intel® H470 (LGA 1200) ATX gaming motherboard with M.2, 10 teamed power stages, Intel® WiFi 6, HDMI, DisplayPort, SATA 6 Gbps, USB 3.2 Gen 2 ports, Thunderbolt™ 3 support, and Aura Sync RGB lighting
award iconaward iconaward icon
Prime X299-A II
Prime X299-A II
Prime X299-A II
Win11
0.0 out of 5 stars.
Intel ATX motherboard LGA 2066 for Intel Core X-series processors, with AI Overclocking, 12 IR3555 power stages, DDR4 4266 MHz, Triple M.2, USB 3.2 Gen 2 Type-C and Aura Sync RGB lighting
award iconaward iconaward icon
Prime X299 Edition 30
Prime X299 Edition 30
Prime X299 Edition 30
Win11
0.0 out of 5 stars.
Intel ATX motherboard LGA 2066 for Intel Core X-series processors with AI Overclocking, 16 IR3555 power stages, DDR4 4266 MHz, Wi-Fi 6, 5 Gbps Ethernet, Type-C Thunderbolt 3 ports, Triple M.2, USB 3.2 front panel connector and Aura Sync RGB lighting
award iconaward iconaward icon
Pro WS C246-ACE
Pro WS C246-ACE
Pro WS C246-ACE
Win11
0.0 out of 5 stars.
Intel LGA 1151 ATX Workstation motherboard with dual Intel LAN, 3 PCIe 3.0, M.2, U.2, SATA, USB Type A&C and ASUS Control Center Express
award iconaward iconaward icon
TUF B365-PLUS GAMING
TUF B365-PLUS GAMING
TUF B365-PLUS GAMING
Win11
0.0 out of 5 stars.
Intel B365 ATX gaming motherboard with 6+2 power stages design, Aura Sync, Aura ARGB header, DDR4 2666MHz support, 32Gbps M.2, and Intel Optane memory ready.
award iconaward iconaward icon
WS Z390 PRO
WS Z390 PRO
WS Z390 PRO
Win11
0.0 out of 5 stars.
Intel LGA 1151 ATX motherboard with AI Overclocking, quad-GPU support, DDR4 4266 MHz, Dual M.2, Intel Optane memory ready, SATA 6Gb/s, USB 3.1 Gen 2 Type-C and front-panel connectors
award iconaward iconaward icon
PRIME X299-DELUXE II
PRIME X299-DELUXE II
PRIME X299-DELUXE II
Win11
0.0 out of 5 stars.
Intel LGA 2066 ATX motherboard with enhanced VRM and M.2 heatsink design, DDR4 4266 (O.C.)MHz, 802.11ac Wi-Fi, triple M.2, Type-C Thunderbolt 3 ports, Intel VROC support
previous image
next image
Related products
previous image
next image
comparison icon
Compare (0)